On April 24, 2025, a joint statement was released by the United Nations, Gavi, and other health organizations to coincide with the start of World Immunization Week, which runs until April 30.

The statement highlighted a troubling global rise in vaccine-preventable diseases such as measles, meningitis, and yellow fever, attributed to misinformation and significant funding cuts.

In light of these challenges, Gavi is preparing for a pledging summit on June 25, 2025, where it seeks at least $9 billion to protect 500 million children and save at least 8 million lives between 2026 and 2030.

Health experts emphasize that immunization remains one of the most cost-effective health interventions, yielding an estimated $54 return for every $1 invested in vaccines.

The agencies are urging parents, the public, and government officials to support immunization efforts and commit to the Immunisation Agenda 2030 (IA2030) for sustained investment in vaccination programs.

UNICEF Executive Director Catherine Russell pointed out a global funding crisis that is severely limiting vaccination efforts for vulnerable children, particularly in fragile countries.

A WHO review indicated that nearly half of the 108 countries surveyed are experiencing moderate to severe disruptions in vaccination efforts due to reduced donor support, impacting over 15 million children.

The 'Big Catch-Up initiative,' launched in 2023, aims to vaccinate children who missed doses during the COVID-19 pandemic, underscoring the need for ongoing investment in immunization.

In 2023 alone, approximately 14.5 million children missed routine vaccinations, with over half of these children living in conflict-affected regions.

The resurgence of diseases like meningitis and yellow fever in Africa, with 124 cases reported in 2024 after a decade of decline, further highlights the urgent need for renewed vaccination efforts.

Dr. Sania Nishtar of Gavi reiterated the necessity for full funding to support targeted vaccine initiatives as the organization prepares for its crucial donor conference.

The ongoing cuts to humanitarian aid, particularly under the current U.S. administration, have further exacerbated the challenges facing global vaccination efforts.