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TSPAN32 Amplifies CAR-T Cell Power: Revolutionizing Cancer Therapy with Enhanced Tumor Killing and Persistence
Scientists have identified TSPAN32 as a key amplifier of CAR-T cell function, enhancing IL-2 receptor signaling and boosting anti-tumor activity. This discovery offers a dual approach for improved CAR-T efficacy through genetic engineering or antibody-mediated upregulation, with potential applications in cancer treatment.
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