Breakthrough Blood Test for Alzheimer's Boasts 91% Accuracy, Slashing Diagnosis Time to Months
July 29, 2024With over 6 million Americans currently affected by Alzheimer's, the demand for early and accurate diagnosis is more pressing than ever.
Researchers in Philadelphia have developed a new blood test that significantly enhances the speed and accuracy of diagnosing Alzheimer's disease.
A recent study involving over 1,200 patients in Sweden found that this blood test achieved an impressive 91% accuracy rate, far surpassing the 61% accuracy of primary care doctors and 73% of specialists.
If widely adopted, these blood tests could reduce the wait time for Alzheimer's treatment eligibility from nearly six years to between six and 13 months.
The incorporation of biochemical markers like p-tau217 into clinical practice may not only enhance diagnosis but also facilitate early treatment initiation for patients.
The p-tau217 biomarker, which correlates with amyloid plaque buildup in the brain, is a key component of the blood test and serves as a strong indicator of Alzheimer's pathology.
Experts, including Professor Jianfeng Feng from Warwick University, have described the blood test as a potential 'breakthrough' that could be integrated into routine screening practices.
However, the widespread use of these blood tests will require further research, established guidelines, and education for physicians.
Traditionally, diagnosing Alzheimer's has relied on invasive methods such as brain scans or spinal taps, which are not always accessible.
Another similar test for p-tau217 has shown even higher accuracy rates, with up to 96% accuracy in identifying elevated beta-amyloid levels.
This development is part of ongoing research efforts aimed at improving diagnostic tools for neurodegenerative diseases.
Neurodegenerative diseases like Alzheimer's involve complex mechanisms, including neuroinflammation and oxidative stress, which complicate diagnosis.
Summary based on 7 sources
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Sources
Yahoo News • Jul 28, 2024
Blood tests for Alzheimer's may be coming to your doctor's office. Here's what to knowCNN • Jul 28, 2024
Alzheimer’s blood test catches 90% of early dementia cases, study findsNBC News • Jul 28, 2024
Blood tests for Alzheimer’s may be coming to your doctor’s office. Here’s what to know