Enhancing mobility emerged as the most favored intervention among older adults across various domains of IC, reflecting demographic trends and the increasing focus on healthy aging practices.

The review emphasizes the necessity for comprehensive intervention strategies that integrate findings across all domains of IC to effectively promote healthy aging.

An umbrella review has been conducted on nonpharmacological interventions aimed at enhancing intrinsic capacity (IC) in older adults, underscoring its importance for healthy aging as recognized by the World Health Organization (WHO).

This comprehensive review synthesized findings from 29 systematic reviews and meta-analyses, encompassing 424 randomized controlled trials and non-RCTs, with a total of 44,825 participants, focusing on interventions in community and outpatient settings.

Among the effective interventions identified, multicomponent physical exercises, such as the 12-week Vivifrail program, have proven beneficial in improving IC, particularly in locomotion, cognition, and vitality among frail older adults.

Intrinsic capacity encompasses several domains, including vitality, locomotor function, cognition, psychological health, and sensory abilities, but there is no consensus on specific dimensions and measurement methods, indicating a need for further research.

While WHO guidelines have been established to manage IC decline through evidence-based interventions, there remains uncertainty regarding the most effective strategies and their implementation.

The review highlights that a significant 67.8% of community-dwelling older adults experience a decline in IC, which raises their risk of frailty and adverse health outcomes, emphasizing the public health implications of IC impairment.

Despite the evidence supporting interventions in locomotor, cognitive, and psychological domains, the effectiveness of sensory interventions remains inconclusive due to a lack of high-quality studies.