A Mass General Brigham study links elevated maternal immune markers to adverse memory effects in offspring, especially postmenopausal women. This 60-year study highlights sex-dependent impacts on aging and Alzheimer's risk, underscoring prenatal immune influence on brain development.

A study shows nicotinamide riboside, a form of vitamin B3, significantly reduces lung inflammation in COPD patients, improving quality of life by lowering IL 8 levels. Researchers urge larger studies to confirm these promising findings and further explore long-term effects on cellular aging.

NFX launches Longevity FAST to fund startups aiming to extend human lifespan beyond 160 years, targeting hardcore longevity breakthroughs. With fast-track funding and mentorship, this initiative supports transformative ideas over incremental biotech advances.

Intensive exercise significantly protects against the decline of nervous tissue associated with aging, according to a new study. The research highlights the role of muscle fibroblasts and stem cells in promoting nerve health and suggests exercise as a potential treatment to maintain muscle and neuronal function.

A Rutgers Health study highlights the long-term cognitive benefits of historical educational policies, revealing a link between mandatory schooling and reduced dementia risk. The research analyzed data from over 20,000 older adults, showing that improved education quality and years of schooling correlate with better memory and verbal fluency, suggesting education investments enhance health equity and cognitive outcomes.

John Mackey, Whole Foods co-founder, unveils Love.Life, a 45,000 sq. ft. wellness club in El Segundo, CA, blending medical care, fitness, and nutrition. The facility offers personalized health solutions, including an app for tracking progress, with memberships starting at $750 monthly.

A new study from Kyushu University suggests that antibodies targeting hepatocyte growth factor (HGF) could help combat age-related muscle atrophy. Researchers identified antibodies that prevent HGF nitration, a process impairing muscle repair, offering hope for effective treatments in Japan's aging society.

Aging neurons are increasingly implicated in Alzheimer's disease, with research highlighting their role in cognitive decline through Tau tangles and amyloid beta accumulation. Studies are also focusing on therapies targeting neuronal aging, offering potential new treatments, backed by the National Natural Science Foundation of China.

Aging significantly impairs muscle regeneration due to cellular changes and satellite cell exhaustion. Research suggests a younger microenvironment might rejuvenate these cells, offering potential for new therapies.

A narrative review reveals strong links between aging hallmarks and sarcopenia, a muscle-wasting disease in humans. Key factors include mitochondrial dysfunction and deregulated nutrient sensing, but more research is needed on the biological pathways.

Recent studies highlight the role of liquid-liquid phase separation (LLPS) in forming membraneless structures that aid cellular functions and link to diseases like neurodegeneration. These findings enhance our understanding of cellular organization and could lead to therapies targeting age-related disorders.

A new study finds that a higher Dietary Diversity Score (DDS) is linked to slower biological aging. Researchers highlight the potential health benefits of a varied diet, though causal conclusions remain elusive.

A Karolinska Institutet study suggests long-term use of certain cardiovascular drugs may reduce dementia risk by up to 25%. The findings highlight the importance of comprehensive management of cardiovascular health in older adults, while also noting potential risks with antiplatelet drugs.

Canvas Medical has unveiled Anova, an EMR system tailored for longevity medicine, designed to optimize clinician workflows and patient engagement. Anova integrates cutting-edge health protocols, supports wearable data, and streamlines prescriptions to enhance care in this innovative specialty.

Dr. Valter Longo's Fasting Mimicking Diet (FMD) claims to mimic fasting benefits like anti-aging and disease prevention without full food abstinence. Research highlights its potential in improving chemotherapy effects, supporting brain health, and managing diabetes, but further studies are needed.

Level 2 of the Ten Levels of Longevity framework emphasizes consumer diagnostics as a key tool for optimizing health and extending vitality through personalized data. Companies like Glycan Age and TruDiagnostic lead the way, despite some diagnostics lacking full clinical validation, with investment opportunities growing in this evolving sector.

Inactivity and aging lead to muscle atrophy and neuromuscular junction (NMJ) instability, primarily due to mitochondrial dysfunction, a new review suggests. Mitochondrial issues in either skeletal muscles or motor terminals might play a pivotal role, highlighting the need for further research.

New research reveals coffee consumption reduces mortality by 17%, potentially extending life by 1.8 years. This benefit is linked to coffee's compounds aiding in stress and inflammation management.

Fight Aging! newsletter will release its November 18, 2024 issue, exploring the science of aging and longevity. Featured topics include immune aging, macrophage behavior in osteoporosis, and hypothalamic neurons' role in longevity.