Biograph, co-founded by Dr. Peter Attia and John Hering, launched in February 2025, offering preventive healthcare focused on healthy aging with annual fees from $7,500 to $15,000. The clinic provides personalized health diagnostics with plans for global expansion, starting with a New York City clinic opening soon.

Longevity.Technology's 2025 survey highlights a push for inclusivity and collaboration in longevity medicine, sponsored by Everest Health. Clinics are eager to share data and standardize practices, despite challenges in technological integration and clinical rigor.

BlueCruise, led by Dr. Tobias Reichmuth and Aleksandra Jovanovic, embarks on an 18-month journey to study longevity in blue zones. Critics question the methodology, but the expedition seeks to gather firsthand data and insights.

University of Houston researchers have pinpointed Fn14 as a key protein for muscle repair, highlighting its role in muscle stem cell stability. This discovery may lead to treatments for muscle-wasting diseases.

Researchers have identified BRD4 as a crucial target for treating spinal disc degeneration, linking it to cell senescence in intervertebral disc degeneration (IDD). The study highlights a signaling axis involving BRD4 and MAP2K7, suggesting potential new drug targets to alleviate age-related back pain.

Genflow Biosciences initiates a pioneering gene therapy trial targeting the SIRT6 gene to address aging in dogs, involving 28 canines over six months. Backed by a $560,000 investment, the study aims to enhance pet well-being and provide insights for human treatments, with results anticipated by late 2025.

A new study links prolonged exposure to high heat with accelerated epigenetic aging in older adults, highlighting potential health risks. Researchers emphasize the need for public health strategies as global temperatures rise.

A PNAS study finds brain aging accelerates at age 44, peaking at 67, with insulin resistance playing a key role. Ketone supplements show promise in reducing brain network disruptions.

Mark Sanborn from the University of Illinois Chicago has launched SenePy, an open-source tool to detect aging cells, which could revolutionize disease treatment. By identifying genetic signatures in tissues, SenePy aids in the study of diseases like Alzheimer's, cancer, and COVID-19, potentially paving the way for new therapies.

Turn Biotechnologies has acquired ARMMs technology from Harvard, boosting its epigenetic reprogramming capabilities. This move enhances their ability to deliver therapies effectively with minimized side effects, advancing their clinical ambitions.

C15:0, a newly recognized essential fatty acid, significantly enhances cellular health and slows biological aging, according to recent studies. Developed with the US Navy, the supplement Fatty15 shows promise in reducing oxidative stress and improving metabolic and cardiovascular health, with 72% of users noticing benefits in 16 weeks.

A groundbreaking study published March 24, 2025, finds that adherence to the AHEI diet can boost the chances of healthy aging by 86% by age 70. The 30-year study highlights the importance of dietary quality, especially as the aging U.S. population faces chronic health conditions.

Joshua McClure of Maxwell Biosciences has unveiled Claromers™, a synthetic peptide designed to combat infectious diseases and potentially increase healthspan by decades. The innovation has attracted a $300 million contract with India and collaboration with the US military, highlighting its promising global health impact.

Human Longevity, Inc. has unveiled a cutting-edge algorithm that significantly enhances early prostate cancer detection, potentially transforming preventive healthcare. By combining whole-genome sequencing, blood marker analysis, and imaging, the company aims to lower costs and improve accessibility, with a bold vision for personalized medicine beyond just prostate cancer.

SRW Laboratories' trial shows its Cel System supplements may reduce biological age and boost health in older adults. Results are promising, but limitations like lack of placebo control require more research.

Fight Aging! newsletter delivers cutting-edge insights on combating age-related diseases to thousands, emphasizing the link between metabolic syndrome, inflammation, and mortality risk. Recent findings highlight therapies like low-frequency ultrasound to combat cellular senescence, offering new hope in the fight against aging.

A UCSF study reveals dormant X chromosome genes can 'reawaken' in older females, boosting cognitive resilience. Findings suggest enhanced PLP1 activity improves cognition and may influence dementia rates.

Cognitive frailty, a syndrome combining physical frailty with cognitive impairment, greatly raises risks of disability and dementia. Experts urge a multidimensional approach to address modifiable risk factors and prevent progression.

TruDiagnostic is transforming personalized nutrition by using biological age data to inform disease risk and nutritional health. Their epigenetic test kits, developed with Longevity Technology, offer insights into lifestyle impacts on aging, aiming for a future where DNA methylation tests rival traditional blood tests in predicting health outcomes.