Seveno Capital, founded by entrepreneur Allen Law, launches with a $70 million investment, targeting health and wellness ventures. Its first investment supports A Cabin Company, which builds nature-centric cabins in Japan to enhance well-being.

Dr. Nitin Shori advocates for integrating health data with clinical insights to empower informed health decisions, emphasizing a shift from reactive to proactive healthcare. This proactive approach could alleviate NHS pressure and highlights the private sector's role in filling preventative care gaps, although regional disparities and funding challenges remain.

M42 and Juvenescence have partnered to boost life sciences research by combining genomics and AI to develop treatments for age-related diseases. Announced at Abu Dhabi Global Health Week, this collaboration reinforces Abu Dhabi's position as a global hub for AI-driven biomedical innovation, focusing on unmet health needs worldwide.

A pivotal study in Aging Cell reveals a direct link between multiple genes and mortality risk, paving the way for new longevity research. The study highlights PDAP1's role in aging, suggesting potential for drug development to enhance lifespan.

RAADfest 2025 marks its 10th anniversary, celebrating radical life extension with events at the Red Rock Casino Resort in Las Vegas this July. The event aims to merge scientific breakthroughs with activism, featuring a new RAD Clinic and focusing on aging as a treatable condition.

General Proximity is pioneering 'induced proximity' medicines, using $16 million in funding to target undruggable proteins for diseases like cancer and neurodegeneration. Their platform maps drug targets to proximity mechanisms, with clinical trials imminent for a promising discovery.

A promising study shows senolytics RG-7112 and o-vanillin significantly reduce low back pain in mice by targeting senescent cells. The treatment also improved disc health and reduced pain markers, suggesting potential for human trials.

The PEARL trial, published in Aging, explored rapamycin's effects on aging, showing it to be generally safe with some benefits in lean tissue mass and pain reduction for women. Conducted by Dr. Zalzala, the study urges further large-scale trials due to its small participant size and self-reporting limitations.

The PEARL trial reveals low-dose rapamycin is safe for healthy aging but doesn't significantly reduce visceral fat. However, women taking 10 mg/week showed increased lean mass and improved quality of life, hinting at potential benefits.

Research on brain aging is advancing with the use of 3D brain models derived from induced pluripotent stem cells, offering a closer mimicry of human brain architecture. These models surpass traditional 2D cultures in studying complex aging processes, aiding in the development of targeted therapies for neurodegenerative disorders.

University of Manchester researchers discovered brain neurons play a crucial role in immune responses during fasting, not just nutrient levels. The study highlights the brain's influence on immune regulation, with implications for treating various health conditions.

Ora Biomedical and Rapamycin Longevity Lab have secured $50,000 to analyze 601 mTOR inhibitors in roundworms, aiming to find compounds more effective than rapamycin. They need an additional $40,000 to complete their study and are using WormBot-AI for high-throughput screening.

A new study in Science Advances unveils a cellular pathway crucial for mitochondrial health, potentially leading to therapies for diseases linked to mitochondrial damage. The research, involving multiple universities, highlights a protein complex that aids in removing damaged mtDNA, promising advancements in preventing conditions like Alzheimer's and Parkinson's.

The documentary 'Fasting and the Longevity Revolution,' inspired by Dr. Valter Longo, is now available on-demand, promoting fasting and a plant-based diet to combat chronic diseases. Directed by Barry Alexander Brown and narrated by Edward Norton, it highlights systemic health issues and supports the Create Cures Foundation.

I Peace unveils My Peace, a service for producing and banking personalized stem cells, at the Vitalist Bay event in California. This innovation allows storing youthful cells for future health therapies.

The Founders Longevity Forum, held on June 10, 2025, at OXO2 in London during London Tech Week, will explore advances in aging-related health technologies. Featuring insights from experts like Brent Hoberman and Laura Deming, the event will cover consumer diagnostics, disease reversal, and AI's role in longevity.

Dr. James DiNicolantonio emphasizes that no single exercise is best for longevity, advocating for a balanced regimen combining resistance, cardiovascular activities, and stretching. His holistic approach aims to enhance mobility, cardiovascular health, bone health, and insulin sensitivity through varied workouts.

Scientists have developed a promising method to reverse aging-related back pain by reprogramming the epigenetics of spinal disc cells using modified exosomes in rats. While successful in these initial tests, further research is needed to assess its viability for human treatments.

The Fight Aging! newsletter emphasizes modern medicine's potential to combat age-related diseases, spotlighting advances in metabolic syndrome, macrophages, and innovative therapies. Recent studies highlight the link between sarcopenia and cardiovascular risks, while gene therapy shows promise in improving brain function and inflammation control.