Researchers are studying aquaporins (AQPs) as potential biomarkers for traumatic brain injury (TBI) to improve patient care.

A study on patients with acute and chronic subdural hematoma found that AQP2 levels correlated with chronic hematoma volume and midline shift, showing promise in chronic cases.

While other AQPs did not show significant links in acute subdural hematoma, AQP2's implications in inflammation and disease severity are being investigated.

AQPs like AQP4, AQP9, AQP1, and AQP2 are being researched for their roles in TBI and intracerebral hemorrhage.

AQP4 is linked to brain edema, AQP9 may aid in water removal, AQP1 is associated with edema formation, and AQP2 could impact astrocyte activation and clinical outcomes.

Understanding the roles of AQPs in TBI is crucial for developing effective therapeutic strategies to manage brain edema and improve patient outcomes.