Cradle Biotech Secures $73M to Revolutionize Protein Engineering with AI

November 26, 2024
Cradle Biotech Secures $73M to Revolutionize Protein Engineering with AI
  • Cradle, a generative AI biotech startup founded in 2021, has successfully raised $73 million in a Series B funding round led by IVP, bringing its total capital raised to over $100 million.

  • Part of the investment will also be used to grow Cradle's wet lab capabilities and engineering team to enhance machine learning functionalities for complex protein tasks.

  • Cradle has established a strong client base, including major pharmaceutical companies like Novo Nordisk and Johnson & Johnson, and is currently working on 31 revenue-generating projects, a significant increase from just four projects a year ago.

  • The company has reported a remarkable 15-fold increase in projects utilizing its platform over the past year, indicating substantial commercial growth.

  • The company plans to allocate the new funding to expand its commercial team, enhance its Amsterdam-based laboratory for better data collection, and improve its computing capabilities.

  • Cradle's generative AI platform allows for faster and more cost-effective protein engineering, achieving cost savings of up to 90% in its R&D processes.

  • One notable success includes a biotechnology client that quadrupled the activity of the P450 enzyme in just three experimental rounds, showcasing the platform's efficiency compared to traditional methods.

  • This funding round comes amid a broader trend of increasing investment in AI-driven pharmaceutical research, with other companies like Basecamp Research and Formation Bio also receiving significant funding.

  • Cradle is part of a growing trend of techbio startups that focus on enhancing drug development through AI, contrasting with older models that aimed to develop drugs independently.

  • CEO Stef van Grieken emphasized the company's mission to address global health challenges using generative AI, with a goal to empower one million scientists worldwide through their software.

  • Research indicates that developing a new drug can cost between $280 million and $380 million, with only 1 in 24 projects succeeding in reaching the market, highlighting the need for innovative solutions like Cradle's.

  • The platform supports a variety of applications, including enzymes, antibodies, peptides, vaccines, and therapeutic proteins, with a current focus on designing optimal enzymes.

Summary based on 7 sources


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