Study Links Heavy Drinking to Increased Dementia Risk: Brain Lesions and Early Death Highlighted

April 13, 2025
Study Links Heavy Drinking to Increased Dementia Risk: Brain Lesions and Early Death Highlighted
  • A recent study published in April 2025 in the journal Neurology reveals that consuming eight or more alcoholic drinks weekly significantly increases the risk of dementia-related brain injuries.

  • Researchers examined the brains of 1,781 deceased individuals, averaging 75 years old, to assess the impact of alcohol on brain health.

  • This increased risk also extends to former heavy drinkers, highlighting a significant correlation between heavy alcohol consumption and dementia.

  • On average, heavy drinkers died 13 years earlier than non-drinkers, underscoring the severe long-term health effects of excessive drinking.

  • The study found that heavy drinkers had a 133% increased likelihood of having brain lesions, which are linked to memory loss and cognitive decline.

  • Moreover, heavy drinkers were found to have a 41% higher likelihood of developing tau tangles, a biomarker associated with Alzheimer's disease.

  • Emergency physician Leana Wen noted that while the findings are compelling, they indicate associations rather than causation, emphasizing the importance of a healthy relationship with alcohol.

  • Dr. Alberto Fernando Oliveira Justo, the study's author, highlighted the public health implications of heavy drinking and the need for preventive measures.

  • The findings reinforce the necessity for public health strategies aimed at reducing heavy drinking and promoting moderation in alcohol consumption.

  • In the study, one alcoholic drink was standardized to 14 grams of alcohol, equivalent to approximately 350 ml of beer, 150 ml of wine, or 45 ml of distilled spirits.

  • While the study suggests a link between heavy drinking and brain injury, it acknowledges limitations, including not assessing participants' health prior to death and lacking details on the duration of alcohol consumption.

  • Participants were categorized into four groups: non-drinkers, moderate drinkers (seven or fewer drinks per week), heavy drinkers (eight or more drinks per week), and former heavy drinkers.

Summary based on 3 sources


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