Breakthrough Human Cell Atlas Unveils New Insights into Disease and Health
November 20, 2024Researchers have unveiled an early map detailing the roles of approximately 37.2 trillion cells in the human body, a significant step forward in understanding human biology.
The findings, marking the release of a first draft of the Human Cell Atlas, were published in the journal Nature on November 20, 2024.
This atlas aims to aid in combating diseases that damage human cells, highlighting the importance of cell health in overall bodily function.
Dr. Timothy Chan from the Cleveland Clinic noted that the atlas not only identifies cell types but also their relationships, offering valuable insights for cancer research.
Understanding the functions of different cell types is crucial for improving knowledge of health and diseases, particularly cancer.
Dr. Ken To emphasized that this atlas could enhance understanding of skeletal conditions in both youth and aging.
Previously thought to consist of around 200 cell types, the project has now identified thousands, linking some to diseases like cystic fibrosis.
The project also revealed insights into human skeletal development, showing how cartilage forms a scaffold for bone growth.
The study focused on specific organs, including the mouth, stomach, and intestines, examining how cells interact and change over time.
Researchers identified a new cell type, gut metaplastic cells, linked to inflammation in individuals suffering from inflammatory bowel diseases.
This ambitious project involves over 3,600 scientists from 100 countries, making it one of the largest biological initiatives since the Human Genome Project.
A more comprehensive atlas is planned for release in 2026, which will include profiles of cells from 18 organs and body systems.
Summary based on 6 sources
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Sources
BBC News • Nov 20, 2024
Human Cell Atlas project transforms understanding of human bodyYahoo News • Nov 20, 2024
Scientists map out the human body one cell at a timeABC News • Nov 20, 2024
Scientists map out the human body one cell at a timeAP News • Nov 20, 2024
Scientists map out the human body one cell at a time