The NFL weekend kicked off with the Jaguars defeating the Patriots in London, wrapping up three weeks of international games.

In an exciting debut for the Buffalo Bills, Amari Cooper, who was recently traded to the team, scored a touchdown on his first catch, contributing to their victory over the Tennessee Titans.

Cleveland Browns running back Nick Chubb made a triumphant return after a lengthy 398-day injury hiatus, scoring a touchdown in his first game back against the Bengals.

Saquon Barkley faced off against his former team, the Giants, rushing for an impressive 176 yards and a touchdown as a member of the Eagles.

Meanwhile, Rams running back Kyren Williams continued his remarkable form, extending his touchdown streak to nine games with two touchdowns against the Raiders, inching closer to the franchise record.

In a significant upset, the Lions handed the Vikings their first loss of the season, leaving the Chiefs as the only undefeated team in the league.

Patrick Mahomes is enjoying a stellar season, starting with a perfect 6-0 record for the first time in his career, adding to his impressive accolades of three Super Bowl wins and two league MVPs.

On a contrasting note, Davante Adams, who recently joined the Jets, had a disappointing performance with only three receptions for 30 yards in a loss to the Steelers.

In a remarkable comeback story, San Francisco 49ers wide receiver Ricky Pearsall played just 50 days after being shot during a robbery, finishing with three receptions for 21 yards.

Buffalo Bills safety Damar Hamlin recorded his second interception of the season, showcasing resilience after overcoming a cardiac arrest incident to start all seven games.