SDFC's first designated player, Chucky Lozano, is expected to make his debut after recovering from an injury, while LAFC will be without forward Jeremy Ebobisse but welcomes back Denis Bouanga from international duty.

LAFC defender Sergi Palencia noted that rivalries are built through competition rather than just geographic proximity, and he anticipates a challenging match against SDFC.

Since 2019, LAFC has shown dominance against expansion teams, outscoring them 15-1, with their latest victory being a 3-0 win over St. Louis City.

San Diego FC (SDFC), the 30th active team in Major League Soccer (MLS), made a strong debut with a 2-0 victory over the LA Galaxy, hinting at the potential for a regional rivalry with LAFC.

Tom Penn, the former president of LAFC and now CEO of SDFC, expressed his excitement for the upcoming match, which will take place at Snapdragon Stadium, a 35,000-seat venue in San Diego.

LAFC head coach Steve Cherundolo, a San Diego native, acknowledges the city's rich soccer history and recognizes SDFC's potential to become a competitive force in the league.

SDFC, looking to bounce back from their first defeat against Austin, currently holds a record of 2 wins, 1 draw, and 2 losses, while LAFC boasts 3 wins and 2 losses.

As SDFC prepares to face LAFC on March 29, 2025, they aim to avoid becoming the seventh MLS expansion team to lose their inaugural match-up against LAFC.

SDFC employs a high-pressing playing style, which LAFC has been preparing for following their recent 2-0 win against Sporting Kansas City.