Akero's Efruxifermin Shows Promise in MASH, Boosts Stocks by 19%
March 4, 2024![Akero's Efruxifermin Shows Promise in MASH, Boosts Stocks by 19%](https://cdn.brief.news/cdn-cgi/image/fit=contain,width=768/images/stories/26a08ba6be04a799111c23efaa445a3d5dcfa949ea924275b3280c8288aef9928d342b9b552fb35ee620ca541b8565c7e1325c4442f5b5aa0cdc55df8942f02e.jpg)
Akero Therapeutics' drug efruxifermin shows promise in reducing liver scarring in MASH patients.
In a mid-stage trial, 75% of patients on a higher dose saw scarring reduction, versus 24% with placebo.
The positive trial results sparked a 19% rise in Akero's stock price.
With no approved drugs for MASH, efruxifermin targets a market that could generate $2-3 billion in peak sales.
Over 17 million Americans are affected by MASH, indicating a significant market need.
The FDA is reviewing a competing drug, but Akero remains confident in efruxifermin's potential.
Multiple companies are in pursuit of MASH treatments, highlighting a competitive landscape.
Summary based on 3 sources
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![Akero's Fatty Liver Disease Drug Lessens Scarring in Mid-stage Trial](https://cdn.brief.news/cdn-cgi/image/fit=contain,width=160/images/links/50778cff6fc073ef79a65824c1d643ee3ab279fcd46cfb8a0a341a13594b9a5adb72e07873da4ab1f8c3d1e08d691db73b02fe2e335cf36ef2512ae98cc4d399.jpg)
Medscape • Mar 4, 2024
Akero's Fatty Liver Disease Drug Lessens Scarring in Mid-stage Trial![Akero returns with more MASH data to back PhIII FGF21 analog drug](https://cdn.brief.news/cdn-cgi/image/fit=contain,width=160/images/links/222364931e0f2bfcdaec2d2a1c4821c10d083937ecfd04d9c34bf9ac07656d6340cf6f916ff6644c33b36478c46bc9f60c471262d9b1eb29c78a8b1d5b77f983.jpg)
Endpoints News • Mar 4, 2024
Akero returns with more MASH data to back PhIII FGF21 analog drug